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Asthma control in Brazil: a systematic review
Juliana S Nakamuta1, Ana Lia Pradella Puglia1, Paula Meireles1
1Novartis Biociências S.A, São Paulo, Brazil.
Summary
Asthma control is a significant challenge in Brazil, with many patients experiencing poorly managed disease despite pharmacotherapy. Further improvements in asthma management strategies are crucial for better patient outcomes in Brazil.
Area of Science:
- Pulmonology
- Public Health
- Clinical Pharmacy
Background:
- Asthma is a prevalent chronic airway inflammatory disease globally.
- Achieving optimal asthma control is challenging due to its personalized nature.
- Studies on asthma control prevalence in Brazil are limited and often based on small samples.
Approach:
- A systematic review was conducted to evaluate asthma control in the Brazilian population.
- Searches included terms for "asthma", "asthma control", and "Brazil" across major databases.
- A narrative synthesis analyzed data from 23 selected studies.
Key Points:
- Studies assessed both pediatric and non-pediatric populations, with a higher female proportion.
- Poorly controlled asthma was linked to severe/persistent disease in children and increased severity in the elderly.
- High rates of exacerbations, hospitalizations, and emergency visits were reported across studies.
Conclusions:
- Asthma control remains a significant challenge in Brazil.
- Despite pharmacotherapy, a notable prevalence of uncontrolled asthma exists.
- There is a clear need for enhanced disease management strategies in Brazil.
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