Atypical CT pattern in multiple sclerosis

We have reported a case of multiple sclerosis in which CT showed a large enhancing lesion with mass effect that was later found to be an acute demyelinating plaque. Magnetic resonance imaging showed other lesions in the centrum semiovale and periventricular areas bilaterally. The advent of magnetic resonance imaging permits diagnosis of atypical demyelinating processes in a less invasive and more direct manner.