Ocular manifestations of COVID-19 in the pediatric age group

Muhannad A Alnahdi1,2,3, Maan Alkharashi4,5,6

  • 1Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.

Insights

COVID-19 can cause various eye problems in children, including conjunctivitis and optic neuritis. These pediatric ocular manifestations, often linked to multisystem inflammatory syndrome in children (MIS-C), generally have positive outcomes with good visual recovery.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Infectious Diseases

Background:

  • COVID-19 is linked to diverse ocular issues, with adult manifestations extensively studied.
  • Pediatric ocular manifestations of COVID-19 and MIS-C require further elucidation.

Purpose of the Study:

  • To comprehensively review and outline pediatric ocular manifestations associated with COVID-19.
  • To differentiate between isolated COVID-19 ocular events and those occurring in MIS-C.

Main Methods:

  • Literature review of reported pediatric ocular manifestations.
  • Categorization of findings based on COVID-19 association and MIS-C.

Main Results:

  • Ocular manifestations occurred across all pediatric age groups (neonates to adolescents).
  • Reported conditions include conjunctivitis, episcleritis, optic neuritis, cranial nerve palsies, retinal vascular events, and orbital inflammation.
  • Conjunctivitis was most frequent in MIS-C (nearly 50%), with other MIS-C ocular findings including uveitis, corneal issues, and retinitis.

Conclusions:

  • Pediatric ocular manifestations of COVID-19 and MIS-C are varied.
  • Most children experience favorable visual outcomes with minimal long-term deficits.
  • Further research is needed to ascertain long-term visual prognosis.

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