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Retrospective study of poisoned patients admitted to a hospital's pediatric intensive care unit in Chile

Nicolás Hormazábal A1, Marcia Yzoard A2,3, Raúl Bustos B4,5

  • 1Químico farmacéutico independiente, Concepción, Chile.

Archivos Argentinos De Pediatria
|July 28, 2022
PubMed

Insights

Pediatric poisoning is a significant concern, with intentional drug overdoses being common in female adolescents. This study analyzed 105 cases at a Chilean pediatric intensive care unit (PICU).

Area of Science:

  • Toxicology
  • Pediatric Critical Care
  • Public Health

Background:

  • Pediatric poisoning represents a global public health challenge.
  • Understanding the specific characteristics of these cases is crucial for targeted interventions.

Purpose of the Study:

  • To characterize pediatric poisoning cases admitted to a pediatric intensive care unit (PICU) in Chile.
  • To identify demographic, etiological, and clinical features of pediatric poisoning.

Main Methods:

  • Retrospective review of medical records for pediatric patients diagnosed with poisoning.
  • Data collected for admissions to the PICU between 2013 and 2017.
  • Analysis of patient demographics, poisoning circumstances, substances involved, and outcomes.

Main Results:

  • 105 pediatric poisoning cases were identified, comprising 3% of PICU admissions.
  • The median age was 10 years, with 73.3% of cases being female.
  • Intentional poisoning accounted for 51% of cases, primarily due to drug exposure (83%), with antidepressants and NSAIDs being most common.

Conclusions:

  • Poisoning cases in the PICU were predominantly intentional, affecting female patients often with a psychiatric history.
  • Antidepressants and non-steroidal anti-inflammatory drugs were the most frequently identified toxic agents.
  • Findings highlight the need for focused prevention strategies and mental health support for at-risk pediatric populations.
Abstract

Keywords:
Chileepidemiologypoisoningtoxicology

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