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Molecular mechanisms and therapeutic effects of different vitamins and minerals in COVID-19 patients

Mohsen Karami Fath1, Malihe Naderi2, Hosna Hamzavi3

  • 1Department of Cellular and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
|July 28, 2022
PubMed

Insights

Maintaining optimal micronutrient intake, including essential vitamins and minerals, is crucial for combating COVID-19. These nutrients support immune function and possess antioxidant properties vital for fighting the virus.

Area of Science:

  • * Nutritional Immunology and Virology

Background:

  • * The global COVID-19 pandemic presents a significant public health challenge with high mortality rates.
  • * Current treatments for COVID-19 are limited, emphasizing supportive care and lacking specific antiviral therapies.
  • * Severe COVID-19 is characterized by oxidative stress and excessive inflammatory cytokine release.

Purpose of the Study:

  • * To review the antiviral properties of various vitamins and minerals.
  • * To explore the correlation between micronutrients and their impact on COVID-19 patients.

Main Methods:

  • * Literature review summarizing existing research on micronutrients and viral infections.
  • * Analysis of the role of essential and trace elements in human health and immune response.
  • * Investigation of antioxidant and anti-inflammatory functions of vitamins and minerals.

Main Results:

  • * Micronutrients, including vitamins (A, B family, C) and minerals (iron, manganese, selenium, zinc, copper), are vital for metabolic processes and immune support.
  • * These nutrients exhibit antioxidant properties, crucial for mitigating oxidative stress observed in severe COVID-19.
  • * Optimal micronutrient levels can modulate inflammation and enhance immune system function.

Conclusions:

  • * Adequate intake of micronutrients, particularly those with antioxidant capabilities, is essential for managing oxidative stress and inflammation in COVID-19.
  • * Vitamins and minerals may play a significant role in both the prevention and treatment strategies for COVID-19.
  • * Further research is warranted to fully elucidate the specific effects of individual micronutrients in COVID-19 patients.

Keywords:
COVID-19Infectious diseaseMineralsSARS-CoV-2Vitamins

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