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Updated: Sep 3, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Published on: August 24, 2013

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Exploring Potential Causal Genes for Uterine Leiomyomas: A Summary Data-Based Mendelian Randomization and FUMA

Yuxin Dai1, Xudong Liu2, Yining Zhu3

  • 1Department of Obstetrics and Gynecology, State Key Laboratory of Complex, Severe and Rare Diseases, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Frontiers in Genetics
|July 29, 2022
PubMed
Summary

This study identified genetic variants and genes potentially causing uterine leiomyomas (ULs) using Mendelian randomization and functional mapping. Key genes like CDC42 and ABCB9 were implicated in UL pathogenesis.

Keywords:
expression quantitative trait locifunctional mappinggenome-wide association studysummary Mendelian randomizationuterine leiomyomas

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