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Published on: November 7, 2017
A Bibliometric and Visualized Analysis of Uremic Cardiomyopathy From 1990 to 2021
Jing-Fu Bao1,2, Pan-Pan Hu1,2, Qin-Ying She3
1State Key Laboratory of Organ Failure Research, National Clinical Research Center for Kidney Disease, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Insights
This bibliometric analysis of uremic cardiomyopathy research reveals key trends over 30 years. Future studies may focus on phosphate metabolism and novel biomarkers for chronic kidney disease patients.
Area of Science:
- Nephrology
- Cardiology
- Bibliometrics
Background:
- Uremic cardiomyopathy is a significant complication of chronic kidney disease (CKD), impacting patient prognosis.
- Research on uremic cardiomyopathy has advanced rapidly but lacks a comprehensive overview.
- This study provides a bibliometric analysis of uremic cardiomyopathy research over the past three decades.
Purpose of the Study:
- To evaluate the research landscape of uremic cardiomyopathy over the last 30 years.
- To identify key topics, significant achievements, and emerging trends in the field.
- To provide insights for future research directions.
Main Methods:
- Bibliometric analysis of 2,403 publications from Science Citation Index Expanded.
- Utilized HistCite, VOSviewer, CiteSpace, and Bibliometrix Package for data analysis and visualization.
- Analyzed publication trends, leading countries, institutions, authors, journals, and keywords.
Main Results:
- The United States leads in productivity and citations; nephrology journals are central.
- Phosphate metabolism and the fibroblast growth factor-23-klotho axis are current research hotspots.
- Research output has plateaued in the last three years.
Conclusions:
- The US and Europe are central to uremic cardiomyopathy research; increased Chinese involvement is suggested.
- Future research may concentrate on endogenous natriuretic factors and novel biomarkers.
- The field is maturing, with established hotspots and emerging areas.
Background:
Uremic cardiomyopathy is commonly presented in chronic kidney disease (CKD), and it severely affects the prognosis of patients with CKD. In the past few decades, the investigation of uremic cardiomyopathy has developed rapidly. However, no report has summarized the situation of uremic cardiomyopathy research to date. This study aimed to evaluate the state of uremic cardiomyopathy research in the last 30 years and identify important topics and achievements, as well as emerging trends through bibliometric analysis.
Materials And Methods:
Publications related to uremic cardiomyopathy were collected from Science Citation Index Expanded. HistCite, VOSviewer, CiteSpace, and the Bibliometrix Package were used for bibliometric analysis and visualization, including the analysis of the overall distribution of the annual publication, leading countries, and active institutions and authors, core journals, co-cited references, and keywords.
Results:
A total of 2,403 studies related to uremic cardiomyopathy were obtained, and progress related to uremic cardiomyopathy was slower in past 3 years. A total of 10,077 authors from 2,697 institutions in 89 countries or regions reported investigations on uremic cardiomyopathy. The United States of America was the most productive and the most cited country. Myles Wolf, Joseph I Shapiro, and Carmine Zoccali published most articles in uremic cardiomyopathy, and journals in nephrology possessed core status in the field. Phosphate metabolism was the hotspot in uremic cardiomyopathy research in recent years, and future progress may concentrate on phosphate metabolism, endogenous natriuretic factors, and novel biomarkers.
Conclusion:
The United States of America and European countries played central roles in uremic cardiomyopathy research, while Chinese scholars should be more involved in this field. Global publications on uremic cardiomyopathy have entered platform stage, and the fibroblast growth factor-23-klotho axis remained a hotspot in this field. Endogenous natriuretic factors and novel biomarkers may be potential directions in future investigations.
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