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Unmet needs and practical solutions in the management of invasive mould infections in Asia

Yee Chun Chen1, Methee Chayakulkeeree2, Arunaloke Chakrabarti3,4

  • 1Division of Infectious Diseases, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

The Journal of Antimicrobial Chemotherapy
|July 29, 2022
PubMed

Insights

Invasive mould infections (IMIs) pose a significant challenge in Asia due to low awareness and limited resources. Urgent action is needed to improve diagnostics, access to antifungals, and local data for better patient outcomes.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Public Health in Asia

Background:

  • Invasive mould infections (IMIs) present significant management challenges in Asia.
  • Low medical practitioner awareness and limited resources exacerbate the difficulties in diagnosis and treatment.
  • Lack of regional data on epidemiology and pathogen identification hinders optimal patient care.

Purpose of the Study:

  • To highlight the unmet needs in managing IMIs across Asia.
  • To advocate for urgent, multi-faceted actions to improve IMI care.
  • To provide a framework for enhancing diagnostic and therapeutic strategies.

Main Methods:

  • This paper is a call to action based on existing knowledge and identified gaps.
  • It synthesizes challenges in awareness, diagnostics, treatment access, and epidemiological data.
  • The approach involves outlining critical areas for improvement in IMI management.

Main Results:

  • Significant gaps exist in awareness, diagnostics, and access to preferred antifungal medications for IMIs in Asia.
  • Limited local epidemiological data complicates the development of effective treatment guidelines.
  • There is a critical need for improved education and cost-effective diagnostic tools.

Conclusions:

  • Urgent improvements in awareness and clinician education regarding IMI 'red flags' are essential.
  • Prioritizing cost-effective rapid diagnostic testing and enhancing access to antifungal medications are crucial.
  • Closing gaps in local epidemiological data is vital for developing region-specific IMI treatment guidelines.

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