Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

9.0K
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
9.0K
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

4.1K
The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
4.1K
Development of the Lymphatic System01:15

Development of the Lymphatic System

1.0K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
1.0K
Introduction to Lymphatic and Immune System01:22

Introduction to Lymphatic and Immune System

6.2K
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are...
6.2K
Overview of the Vascular System01:20

Overview of the Vascular System

2.9K
The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
2.9K
Fluid Connective Tissues: Blood and Lymph01:20

Fluid Connective Tissues: Blood and Lymph

15.0K
Blood and lymph are fluid connective tissues. They contain cells, also known as formed elements, circulating in a liquid extracellular matrix, the plasma. The formed elements are derived from hematopoietic stem cells in the bone marrow. Blood and lymph connect all vital parts and carry nutrients, oxygen, and other essential molecules like antibodies.
Blood
The blood flows through blood vessels— arteries, capillaries, and veins. Blood plasma is primarily made of proteins, solutes, and...
15.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The potential of a selective anxiolytic afobazole in clinical practice].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Transitional cognitive syndrome: Reconsidered classification of cognitive disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Rapidly progressive cognitive impairment as a single clinical manifestation of anti-NMDA receptor encephalitis].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[New Opportunities in the Treatment of Moderate Cognitive Impairment: Results of the Millennium Study in Real Clinical Practice].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[Clinical and kinematic analysis of swimming disorders in Parkinson's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same author

[The patient pathway in the diagnosis and treatment of mild cognitive impairment and new therapeutic opportunities. Resolution of the Expert Council (Moscow, April 21, 2025)].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2025
Same journal

[The role of the cerebellum in the coordination of brain activity and the development of autism spectrum disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[A clinical case of anxiety-hypochondriacal depression with extensive somatized symptoms in the elderly].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[De novo variant in the ATP2B2 gene as a cause of neuropsychiatric developmental disorder].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[Electroencephalographic predictors of olfactory stimulus discrimination in COVID-19 survivors].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[Effect of long-term carbamazepine therapy on bone metabolism in women with epilepsy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
Same journal

[Glial-derived neurotrophic factor and neuropsychological status in COVID-19 survivors].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026
See all related articles

Related Experiment Video

Updated: Sep 3, 2025

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
10:05

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy

Published on: May 22, 2020

10.4K

[Glymphatic system].

N G Dudchenko1, A Sh Chimagomedova1, E E Vasenina1

  • 1Russian Medical Academy of Continuous Professional Education, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|July 29, 2022
PubMed
Summary
This summary is machine-generated.

The glymphatic system clears brain waste and regulates solutes. Its dysfunction is linked to central nervous system diseases, highlighting its critical role in brain health.

Keywords:
aquaporin-4cerebrospinal fluidglymphatic clearanceglymphatic systemperavascular spaces

More Related Videos

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
06:22

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

Published on: July 29, 2019

14.0K
Cannula Implantation into the Cisterna Magna of Rodents
10:13

Cannula Implantation into the Cisterna Magna of Rodents

Published on: May 23, 2018

45.9K

Related Experiment Videos

Last Updated: Sep 3, 2025

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
10:05

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy

Published on: May 22, 2020

10.4K
In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
06:22

In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

Published on: July 29, 2019

14.0K
Cannula Implantation into the Cisterna Magna of Rodents
10:13

Cannula Implantation into the Cisterna Magna of Rodents

Published on: May 23, 2018

45.9K

Area of Science:

  • Neuroscience
  • Physiology
  • Cellular Biology

Background:

  • The glymphatic system is a recently discovered brain waste clearance pathway.
  • It plays a crucial role in maintaining solute balance within the central nervous system.

Purpose of the Study:

  • To review current understanding of glymphatic system anatomy and physiology.
  • To explore factors regulating glymphatic flow.
  • To examine the link between glymphatic dysfunction and CNS pathology.

Main Methods:

  • Literature review of modern scientific views.
  • Analysis of factors influencing glymphatic transport.
  • Correlation of glymphatic system function with neurological diseases.

Main Results:

  • Detailed overview of glymphatic system structure and function.
  • Identification of key regulators of glymphatic flow.
  • Established connection between impaired glymphatic system and CNS disorders.

Conclusions:

  • The glymphatic system is vital for brain homeostasis.
  • Dysfunction of this system contributes to the pathogenesis of neurological conditions.
  • Further research into the glymphatic system is essential for understanding and treating brain diseases.