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Updated: Sep 3, 2025

Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication
Published on: June 5, 2016
Gaining insights into the internal states of the rodent brain through vocal communications
1Division of Biology and Biological Engineering 140-18, TianQiao and Chrissy Chen Institute for Neuroscience, California Institute of Technology, Pasadena, CA 91125, USA; Kennedy Krieger Institute, Baltimore, MD 21205, USA; The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Abstract:
Animals display various behaviors during social interactions. Social behaviors have been proposed to be driven by the internal states of the animals that reflect their emotional or motivational states. However, the internal states that drive social behaviors are complex and are often difficult to interpret. Many animals species, such as rodents, use vocalizations for communication in various social contexts. This review provides an overview of the current understanding of mouse vocal communications, its underlying neural circuitry, and the potential to use vocal communications as a readout for the animal's internal states during social interactions.

