[Exocrine pancreas insufficiency in primary sclerosing cholangitis]

In 8 patients with primary sclerosing cholangitis, special pancreatic diagnostic procedures were performed. Exocrine pancreatic insufficiency was established by means of the secretin-pancreozymin test in 3 patients, in 2 of whom ERCP revealed pancreatic duct changes. None of them suffered from the characteristic pain of chronic pancreatitis. Involvement of the pancreas in primary sclerosing cholangitis should be considered as cause of diarrhoea or steatorrhoea in this disease of the biliary tract.