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Related Experiment Video

Updated: Sep 3, 2025

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
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Postdischarge Nutrition in Preterm Infants.

Allan Lucas1, Jan Sherman2, Mary Fewtrell1

  • 1UCL Great Ormond Street Institute of Child Health, London, UK.

Neoreviews
|July 31, 2022
PubMed
Summary
This summary is machine-generated.

Postdischarge nutrition for preterm infants is crucial. Reviewing randomized controlled trials (RCTs) clarifies the benefits of specialized nutrition for growth and neurodevelopment in these vulnerable infants.

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Area of Science:

  • Neonatal nutrition
  • Pediatric growth and development

Background:

  • Preterm infants often experience growth restriction and undernutrition post-discharge.
  • Standard infant diets may not meet the specific nutritional needs of preterm infants.

Purpose of the Study:

  • To review and reanalyze existing evidence on postdischarge nutrition for preterm infants.
  • To clarify the strengths and limitations of current research.
  • To provide guidance for optimizing postdischarge nutritional strategies.

Main Methods:

  • Systematic review and reanalysis of randomized controlled trials (RCTs).
  • Inclusion of observational data linking growth to neurodevelopment.
  • Examination of evidence on growth, bone mineralization, and neurocognitive function.

Main Results:

  • Evidence from RCTs suggests nutritional fortification may positively impact postdischarge growth.
  • Research explores the quality of growth and bone mineralization.
  • Potential effects on neurocognitive function are being investigated.

Conclusions:

  • Interpreting postdischarge nutrition data for preterm infants remains challenging.
  • Further clarity is needed to positively impact clinical practice.
  • This review aims to enhance the understanding and application of evidence-based nutrition.