[Detection of immunoglobulins in cervical secretions in an inflammatory adnexal process]

Single radial immunodiffusion test was used for estimations of IgG, M, A and secretory immunoglobulin A (S-IgA) in cervical secretions of patients with pelvic inflammations. Salpingo-oophoritis was diagnosed and staged by laparoscopy and an activity index aimed controlling the during therapy and decreased after therapy, but the decrease after therapy was significant for IgA only. Immunoglobulin values before and after therapy were as follows: IgG (mean = 0.63 g/l, s = 0.54, n = 32 and x = 0.24 g/l, s = 0.27, n = 7), IgM (mean = 0.028 g/l, s = 0.028, n = 33 and mean = 0.17 g/l, s = 0.023, n = 7), IgA (mean = 0.12 g/l, s = 0.09, n = 30 and mean = 0.04 g/l, s = 0.035, n = 7), S-IgA (mean = 0.77 g/l, s = 0.66 n = 30 and mean = 0.28 g/l, s = 0.41, n = 7). In no case we found an S-IgA deficiency. On the other side IgM could not be estimated in cervical secretions of 8 patients with long time applicated intrauterine device. Therefore IgM in cervical secretions may be a sign of acute ascending inflammations.