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Daily Reports on Phage-Host Interactions.

Kamil Albrycht¹, Adam A Rynkiewicz¹, Michal Harasymczuk²

¹Department of Computational Biology, Faculty of Biology, Adam Mickiewicz University, Poznań, Poland.

Frontiers in Microbiology

|August 1, 2022

Summary

This study introduces Phage & Host Daily (PHD), a web tool cataloging phage-host interactions. PHD consolidates data from multiple sources, providing an accessible resource for researchers studying bacterial and archaeal viruses.

Keywords:

archaea bacteria database host phage phage-host interactions web application

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Area of Science:

Virology
Microbiology
Bioinformatics

Background:

Understanding phage-host interactions is vital for virus biology, biotechnology, and medicine.
Existing data on phage-host ranges are fragmented across numerous databases, hindering accessibility.
A centralized, up-to-date resource is needed to consolidate this scattered information.

Purpose of the Study:

To develop a comprehensive and continuously updated web application for phage-host associations.
To provide researchers with a tool to easily identify viruses targeting specific bacterial and archaeal taxa.
To facilitate the study of virus diversity and host specificity.

Main Methods:

Developed the Phage & Host Daily (PHD) web application.
Integrated data from seven distinct source databases on virus-host interactions.
Incorporated current taxonomic classifications from official maintenance groups.
Implemented daily updates to ensure data freshness.

Main Results:

PHD offers a centralized catalog of known phage-host associations.
The application allows users to query viruses based on specific bacterial and archaeal hosts.
Provides summary statistics on host/virus diversity, interactions, and phage host ranges.
The resource is updated daily, ensuring access to the latest information.

Conclusions:

PHD serves as a valuable, consolidated resource for phage-host relationship research.
The tool enhances accessibility to critical data for virology and applied phage research.
Daily updates ensure the catalog remains current and relevant for scientific inquiry.