Isolated extreme right ventricular hypertrophy: A case report

Area of Science:

• Cardiology
• Cardiovascular Imaging
• Genetics

Background:

• Hypertrophic cardiomyopathy (HCM) is typically characterized by left ventricular (LV) hypertrophy.
• Right ventricular (RV) involvement can occur but is usually less severe than LV hypertrophy.

Observation:

• A 72-year-old male presented with an abnormal electrocardiogram.
• Echocardiography revealed isolated hypertrophy of the RV apex.
• Multidetector computed tomography showed partial calcification within the RV hypertrophy, surrounded by hypoperfused myocardium.

Findings:

• Diagnosis of HCM was confirmed based on myocardial imaging characteristics, including systolic thickening.
• The patient exhibited an extreme RV hypertrophy with a maximum wall thickness of 40 mm.
• This case represents an isolated extreme RV HCM phenotype.

Implications:

• This case underscores the importance of recognizing diverse phenotypes in HCM.
• It highlights the possibility of isolated and extreme RV hypertrophy as a presentation of HCM.
• Awareness of such presentations is crucial for accurate diagnosis and management of hypertrophic cardiomyopathy.