Related Experiment Video
Updated: Sep 2, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
First Case of Pyogenic Spondylodiscitis Caused by Gemella sanguinis
Kunihiko Hashimoto1,2, Eiji Wada1,2, Kazuma Kitaguchi1,2
1Department of Orthopedic Surgery, Osaka Police Hospital, Osaka, JPN.
Abstract:
A 78-year-old man presented with back pain. Magnetic resonance imaging revealed marrow edema within the L4 and L5 vertebral bodies and a spinal epidural abscess in the spinal canal. The patient was considered to have pyogenic spondylodiscitis at the L4/L5 level. The Gram-positive cocci isolated from blood cultures were subsequently identified as Gemella sanguinis using matrix-assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS). Symptom improvement was achieved and the infection was eradicated with conservative treatment (treatment with ceftriaxone [CTRX] and minocycline [MINO]). We report the first case of G. sanguinis-associated pyogenic spondylodiscitis. MALDI-TOF MS was useful in identifying this uncommon bacterium.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction
Bacterial Phylum Spirochaetes
Endocarditis II: Clinical Features of Infective Endocarditis

