Related Experiment Video
Updated: Sep 2, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Predicting the Success Rate of Elective Percutaneous Coronary Intervention for Prior Failed Chronic Total Occlusion:
Wenzheng Li1, Zheng Wu1, Hongyu Peng1
1Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Insights
A new scoring system accurately predicts success for re-attempting percutaneous coronary intervention (PCI) in chronic total occlusions (CTO). Factors like lesion length and retrograde approach significantly influence PCI success rates.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Imaging
Background:
- Chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has a significant failure rate.
- Predicting success for re-attempting CTO-PCI is crucial for patient management and resource allocation.
Purpose of the Study:
- To develop and validate a scoring system for predicting the technical success of re-attempting PCI in patients with CTO.
- Identify key predictors of successful CTO-PCI re-intervention.
Main Methods:
- Retrospective analysis of 194 patients who underwent attempted CTO-PCI between January 2016 and December 2019.
- Multivariate logistic regression analysis to identify predictors of technical success.
- Development of a scoring system based on identified predictors.
Main Results:
- Key predictors of successful re-attempt CTO-PCI include occlusion length < 20 mm, non-calcification, adequate distal landing zone, Rentrop grade ≥ 2, and initial retrograde approach.
- The scoring system demonstrated increasing technical success rates with higher scores (0% for score 0 to 93.3% for score ≥ 4).
Conclusions:
- The developed scoring system effectively predicts the likelihood of technical success for re-attempting CTO-PCI.
- This tool can aid clinicians in decision-making and patient selection for complex PCI procedures.
Abstract:
To investigate a scoring system for predicting the risk of successful percutaneous coronary intervention (PCI) after prior failed chronic total occlusion (CTO). Patients with previously attempted CTO-PCI were enrolled in our study retrospectively from January 2016 to December 2019. All clinical and procedural data were collected and analyzed. Univariate and multivariate logistic regression was performed to investigate the predictors of technical success. A total of 194 patients/CTO lesions were studied. The multivariate logistic regression showed that occlusion length < 20 mm (odds ratio (OR) = 2.94, score = 1), non-calcification (OR = 2.93, score = 1), adequate distal landing zone (OR = 4.46, score = 1), Rentrop grade ≥ 2 (OR = 5.98, score = 1), and retrograde approach as the initial strategy (OR = 10.28, score = 2) were predictors of the success of re-attempt PCI. The technical success rate for scores from 0 to ≥ 4 were 0%, 17.9%, 46.2%, 77.8%, and 93.3% respectively. Our scoring system can be used to predict the success rate of re-attempt CTO-PCI.
More Related Videos
07:25Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
10:03Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Related Concept Videos
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Acute Coronary Syndrome III: Diagnostic Studies
Acute Coronary Syndrome IV: Interprofessional Care
Coronary Artery Disease V: Interprofessional Care