Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Sep 2, 2025

A Heterotopic Mouse Model for Studying Laryngeal Transplantation
14:15

A Heterotopic Mouse Model for Studying Laryngeal Transplantation

Published on: January 13, 2023

2.9K

Proposal for an algorithm to avoid neck dissection during salvage total laryngectomy. A GETTEC multicentric study.

Romain Dassé1, Charles Dupin2, Philippe Gorphe3

  • 1Department of Head and Neck Surgery, Bordeaux University Hospital, F33000 Bordeaux, France.

Oral Oncology
|August 1, 2022
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility of Early Activation of a Cochlear Implant: Study of Electrophysiology, Audiometry, and Patient Satisfaction Data.

Journal of neurological surgery. Part B, Skull base·2026
Same author

Defining physician acceptance of radiosensitivity testing for guiding therapeutic interventions in head and neck cancer: A Delphi consensus study.

Clinical and translational radiation oncology·2026
Same author

Safe Omission of Postoperative Neck Irradiation in Selected pN0 Patients With Locally Advanced Oral Cavity Squamous Cell Carcinoma.

Head & neck·2026
Same author

Usefulness of routine clinical follow-up after oral cavity cancer treatment: a single-center retrospective study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Design and Scalable Fabrication of Bioactive Ti/Polymer/Ti Sandwich Composites with Controlled Mechanics for Cranioplasty.

ACS biomaterials science & engineering·2026
Same author

Reduced Morphine Consumption with Photobiomodulation in Head and Neck Cancer: A Matched Cohort of 280 Cases.

Photobiomodulation, photomedicine, and laser surgery·2026
This summary is machine-generated.

Salvage total laryngectomy (STL) in patients with recurrent laryngeal cancer (rcN0) showed occult metastases in 9.1%. Neck dissection (ND) is not associated with survival benefits and increases complications, suggesting selective ND use.

Area of Science:

  • Head and Neck Surgery
  • Oncology
  • Laryngeal Cancer Research

Background:

  • Laryngeal squamous cell carcinoma (LSCC) treatment often involves radiotherapy.
  • Salvage total laryngectomy (STL) is a treatment option for recurrent LSCC.
  • Determining the need for neck dissection (ND) in recurrent cases (rcN0) is crucial.

Purpose of the Study:

  • Identify factors associated with occult metastases before STL in rcN0 patients.
  • Develop an algorithm to select patients not requiring ND.
  • Reduce unnecessary morbidity from ND procedures.

Main Methods:

  • Multicentric retrospective study (2008-2018) involving five centers.
  • Inclusion criteria: prior radiotherapy for LSCC, STL with or without ND, and rcN0 neck.
Keywords:
Neck dissectionOccult metastasisSalvage total laryngectomy

More Related Videos

Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy
09:04

Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy

Published on: September 11, 2021

3.0K
Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

8.2K

Related Experiment Videos

Last Updated: Sep 2, 2025

A Heterotopic Mouse Model for Studying Laryngeal Transplantation
14:15

A Heterotopic Mouse Model for Studying Laryngeal Transplantation

Published on: January 13, 2023

2.9K
Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy
09:04

Low-Cost Single-Port LoCoSP Device for a Transcervical Approach in Minimally Invasive Transhiatal Esophagectomy

Published on: September 11, 2021

3.0K
Learning Modern Laryngeal Surgery in a Dissection Laboratory
07:30

Learning Modern Laryngeal Surgery in a Dissection Laboratory

Published on: March 18, 2020

8.2K
  • Analysis of occult metastases, survival, and complications based on ND status.

    • Main Results:

    • Overall occult metastases rate was 9.1% in rcN0 patients.
    • Higher rates of occult metastases were linked to initial cN+ status and advanced recurrent T stages (rcT3-T4).
    • No significant difference in overall survival between patients with or without ND; higher complication rates in the ND group.

    Conclusions:

    • Neck dissection (ND) does not improve survival and is linked to significant complications.
    • STL without ND may be suitable for select patients (rcT1-T2 or rcT3-T4 with >12-month recurrence).
    • A validated algorithm could potentially avoid 58% of ND procedures, reducing morbidity.