Related Experiment Video
Updated: Sep 2, 2025
07:33
A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
21.4K
Granulomatosis with polyangiitis presenting with intestinal obstruction: A case report
Reem Alawna1, Tala Jalamneh1, Maram Massad1
1Jenin Governmental Hospital, Jenin, West Bank, Palestine.
International Journal of Surgery Case Reports
|August 1, 2022
Summary
Granulomatosis with polyangiitis (GPA) rarely causes intestinal obstruction, typically due to perforation. This case highlights a unique instance of GPA-related intestinal obstruction without perforation, managed conservatively.
Area of Science:
- Rheumatology
- Gastroenterology
- Vasculitis Research
Background:
- Granulomatosis with polyangiitis (GPA) is a rare systemic vasculitis.
- Gastrointestinal (GI) manifestations are uncommon in GPA, occurring in 5-10% of patients.
- Intestinal obstruction is a rare GI complication, historically linked to bowel perforation.
Purpose of the Study:
- To report a novel case of intestinal obstruction in a patient with GPA.
- To describe an unusual presentation of GPA-related intestinal obstruction without perforation.
- To evaluate conservative management strategies for this rare complication.
Main Methods:
- Case report of a 14-year-old female with known GPA.
- Presentation with symptoms of intestinal obstruction.
- Conservative treatment approach implemented.
Main Results:
- The patient experienced intestinal obstruction without evidence of bowel perforation.
- Conservative management was successful in resolving the obstruction.
- This represents a new pattern of GI complication in GPA.
Conclusions:
- Intestinal obstruction can occur in GPA without perforation.
- This presentation expands the spectrum of GI involvement in GPA.
- Conservative management is a viable therapeutic option for GPA-associated intestinal obstruction without perforation.
