Related Experiment Video
Updated: Sep 2, 2025
11:22
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
29.2K
Potential relationship between Tourette syndrome and gut microbiome
Junze Geng1, Can Liu1, Jingyu Xu1
1First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
Jornal De Pediatria
|August 1, 2022
Summary
Altering gut microbiota may impact Tourette syndrome severity. Research suggests a connection between gut bacteria and neurological disorders, offering new treatment avenues like probiotics.
Area of Science:
- Neurology
- Microbiology
- Gastroenterology
Background:
- Tourette syndrome is a chronic neurological disorder impacting children's quality of life.
- The brain-gut axis, a communication pathway between the gut microbiome and the brain, is increasingly recognized for its role in neurological and psychiatric conditions.
Purpose of the Study:
- To review the relationship between gut microbiota and Tourette syndrome.
- To explore if gut microbiota alterations influence Tourette syndrome severity.
Main Methods:
- A literature review of studies from PubMed, Google Scholar, and CNKI.
- Inclusion of original research and review articles published up to May 2022.
Main Results:
- Studies indicate a potential interaction within the brain-gut axis relevant to Tourette syndrome.
- Specific gut microbiota changes, including increased Ruminococcaceae and Bacteroides, are observed in Tourette syndrome patients.
- Preliminary evidence suggests probiotics and fecal microbial transplantation may offer therapeutic benefits for Tourette syndrome, particularly drug-resistant cases.
Conclusions:
- The gut microbiota-Tourette syndrome connection is an emerging area requiring further investigation.
- Larger sample sizes and in-depth research are needed to fully elucidate this relationship and its therapeutic potential.
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