Related Experiment Video
Updated: Sep 2, 2025
10:32
A Universal Protocol for Large-scale gRNA Library Production from any DNA Source
Published on: December 6, 2017
11.2K
Kinugasa Reaction for DNA-Encoded β-Lactam Library Synthesis
Ayun Luo1, Ziqi Zhang1, Fanming Zeng1
1Pharmaron (Ningbo) Technology Development Co., Ltd., No. 800 Bin-Hai 4th Road, Hangzhou Bay New Zone, Ningbo, 315336China.
Organic Letters
|August 2, 2022
Abstract:
β-Lactam antibiotics are one of the most important antibacterial drug classes worldwide. This work will present the first prototype on-DNA β-lactam combinatorial library with novel structures and chemical space properties that would be significant for phenotypic screening to identify the next generation of antibiotics to combat the pervasive problem of bacterial resistance.
