Related Experiment Video

Updated: Sep 2, 2025

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
09:02

Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population

Published on: January 31, 2025

610

Hospitalizations for major osteoporotic fractures in Switzerland: a long-term trend analysis between 1998 and 2018

Kurt Lippuner1, Gergana Rimmer2, Anna K Stuck3

  • 1Department of Osteoporosis, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. kurt.lippuner@insel.ch.

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
|August 2, 2022
PubMed

Insights

Hospitalizations for major osteoporotic fractures (MOF) increased in Switzerland from 1998-2018. This rise was driven by more spine, humerus, and radius fractures, while hip fracture incidence decreased in both men and women.

Area of Science:

  • Orthopedics
  • Epidemiology
  • Gerontology

Background:

  • Long-term epidemiological trends of major osteoporotic fractures (MOF) in Switzerland remain largely unknown.
  • Understanding these trends is crucial for public health planning and resource allocation.

Purpose of the Study:

  • To analyze the epidemiological trends of hospitalizations for MOF in Switzerland between 1998 and 2018.
  • To investigate changes in the incidence of specific fracture types (hip, spine, proximal humerus, distal radius) and their impact on healthcare utilization.

Main Methods:

  • Utilized data from the Swiss Federal Office of Statistics on acute hospitalizations for MOF.
  • Calculated age-standardized incidence rates using 1998 as the reference year.
  • Analyzed trends in the mean length of acute hospital stays for MOF.

Main Results:

  • Overall MOF hospitalizations increased by 68.2% in men and 46.2% in women.
  • Age-standardized incidence of MOF rose by 5.7% in men and 5.1% in women.
  • Hip fracture incidence decreased significantly (15.3% in men, 21.5% in women), while other MOF incidence increased substantially (31.8% in men, 40.1% in women).
  • Mean length of hospital stay for MOF decreased by approximately 50% for both sexes.

Conclusions:

  • The increase in MOF hospitalizations in Switzerland is not solely due to population aging.
  • The trend is driven by a rise in non-hip fractures, with a concurrent decrease in hip fractures.
  • These findings highlight a significant shift in osteoporotic fracture patterns, necessitating updated prevention and management strategies.

Keywords:
EpidemiologyHip fracturesMajor osteoporotic fracturesOsteoporosisSwitzerland

More Related Videos

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model07:12

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Published on: September 28, 2017

8.3K
Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position06:58

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position

Published on: August 17, 2017

10.1K

Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.9K
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.1K
Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
3.6K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
2.2K
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
38.5K