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Imaging of antitubercular dimeric boronic acids at the mycobacterial cell surface by click-probe capture

Collette S Guy1, Ruben M F Tomás2,3, Qiao Tang2

  • 1School of Life Sciences, University of Warwick, Coventry, CV4 7AL, UK. e.fullam@warwick.ac.uk.

Chemical Communications (Cambridge, England)
|August 2, 2022
PubMed

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...