Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Thermal and Photochemical Electrocyclic Reactions: Overview01:26

Thermal and Photochemical Electrocyclic Reactions: Overview

2.4K
Electrocyclic reactions are reversible reactions. They involve an intramolecular cyclization or ring-opening of a conjugated polyene. Shown below are two examples of electrocyclic reactions. In the first reaction, the formation of the cyclic product is favored. In contrast, in the second reaction, ring-opening is favored due to the high ring strain associated with cyclobutene formation.
2.4K
Radical Reactivity: Overview01:11

Radical Reactivity: Overview

2.1K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.1K
Redox Equilibria: Overview01:23

Redox Equilibria: Overview

628
A reduction-oxidation reaction is commonly called a redox reaction. In a redox reaction, electrons are transferred from one species to another rather than being shared between or among atoms. The reducing agent or reductant is the species that loses electrons and gets oxidized in the process. The species that gains electrons and gets reduced in the process is the oxidizing agent or oxidant. Redox reactions are represented as two separate equations called half-reactions, where one equation...
628
Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

2.4K
The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the...
2.4K
Pericyclic Reactions: Introduction01:17

Pericyclic Reactions: Introduction

8.5K
Pericyclic reactions are organic reactions that occur via a concerted mechanism without generating any intermediates. The reactions proceed through the movement of electrons in a closed loop to form a cyclic transition state, where rearrangement of the σ and π bonds yields specific products.
Pericyclic reactions can be classified into three categories: electrocyclic reactions, cycloaddition reactions, and sigmatropic rearrangements. Electrocyclic reactions and sigmatropic...
8.5K
Redox Reactions01:27

Redox Reactions

102
Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
102

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative Photoswitching of Spin States in o-Fluoroazobenzene-Loaded Metal-Organic Frameworks.

Angewandte Chemie (International ed. in English)·2026
Same author

Breaking the methanol/dimethyl carbonate azeotrope using a metal-organic framework with tetrahedral potassium-ion cluster gates.

Nature chemistry·2026
Same author

Chiral Dysprosium Single-Molecule Magnets Displaying Circular Polarized Luminescence and Magneto-Chiral Dichroism.

Angewandte Chemie (International ed. in English)·2026
Same author

Strongly axial monodentate carboxylate for dysprosium single-ion magnets.

Dalton transactions (Cambridge, England : 2003)·2026
Same author

Fe metal-organic framework-derived heterojunction for metabolic diagnosis of thymic epithelial tumor.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Benchmark Performance of One-Step Ethylene Separation: From Optimized Crystal Synthesis to Quantitative Mixture Breakthrough Experiment and Simulation.

Journal of the American Chemical Society·2026

Related Experiment Video

Updated: Sep 2, 2025

Author Spotlight: Magnetometric Characterization of Intermediates in the Solid-State Electrochemistry of Redox-Active Metal-Organic Frameworks
06:53

Author Spotlight: Magnetometric Characterization of Intermediates in the Solid-State Electrochemistry of Redox-Active Metal-Organic Frameworks

Published on: June 9, 2023

2.1K

Redox-Programmable Spin-Crossover Behaviors in a Cationic Framework.

Si-Guo Wu1, Long-Fei Wang1, Ze-Yu Ruan1

  • 1Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education, School of Chemistry, Sun Yat-Sen University, 510275 Guangzhou, Guangdong, P. R. China.

Journal of the American Chemical Society
|August 2, 2022
PubMed
Summary
This summary is machine-generated.

This study presents a novel cationic metal-organic framework (MOF) exhibiting switchable spin-crossover (SCO) behavior. Chemical redox reactions enable precise control over multi-step SCO dynamics, paving the way for advanced molecular switches.

More Related Videos

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

10.7K
Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals
10:35

Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals

Published on: May 29, 2018

8.8K

Related Experiment Videos

Last Updated: Sep 2, 2025

Author Spotlight: Magnetometric Characterization of Intermediates in the Solid-State Electrochemistry of Redox-Active Metal-Organic Frameworks
06:53

Author Spotlight: Magnetometric Characterization of Intermediates in the Solid-State Electrochemistry of Redox-Active Metal-Organic Frameworks

Published on: June 9, 2023

2.1K
Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

10.7K
Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals
10:35

Novel Techniques for Observing Structural Dynamics of Photoresponsive Liquid Crystals

Published on: May 29, 2018

8.8K

Area of Science:

  • Materials Science
  • Inorganic Chemistry
  • Supramolecular Chemistry

Background:

  • Metal-organic frameworks (MOFs) are versatile platforms for creating multi-responsive materials.
  • Spin-crossover (SCO) materials exhibit tunable magnetic properties based on external stimuli.

Purpose of the Study:

  • To synthesize a novel cationic MOF with hysteretic spin-crossover behavior.
  • To investigate the redox-programmable capability of the MOF for manipulating SCO dynamics.
  • To explore the potential of MOFs as multi-responsive molecular switches.

Main Methods:

  • Synthesis of a cationic MOF incorporating a neutral tetradentate ligand and a dicyanoaurate(I) anion.
  • Post-synthetic modification via oxidation of gold(I) to gold(III) centers.
  • Redox manipulation using l-ascorbic acid to revert SCO behavior.
  • Periodic Density Functional Theory (DFT) calculations to rationalize experimental observations.

Main Results:

  • A rare cationic MOF, [FeII(TPB){AuI(CN)2}]I·4H2O·4DMF, exhibiting hysteretic SCO near room temperature was synthesized.
  • The MOF demonstrated redox-programmable responses to dihalogen molecules.
  • Oxidation of Au(I) linkers led to a switch from one-step to two-step (Br2) or three-step (I2) hysteretic SCO.
  • Reduction by l-ascorbic acid successfully reverted the SCO behavior to a one-step process.

Conclusions:

  • This work demonstrates the first instance of switchable one-/two-/three-stepped SCO dynamics controlled by chemical redox reactions.
  • The developed MOF offers a new platform for designing multi-responsive molecular switches with tunable dynamics.
  • The findings open new perspectives in the field of responsive materials and molecular electronics.