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Effect of Post-Transplant Cardiac Angiographic Procedures on Post-Transplant Renal Function
Suzan Keskin1, Orçun Çiftci1, Ebru Ayvazoğlu Soy2
1Department of Cardiology, Başkent University Faculty of Medicine, Ankara, Turkey.
Transplantation Proceedings
|August 2, 2022
Summary
Cardiac interventions after kidney transplants negatively impact renal function. Procedures like stenting or bypass surgery reduced kidney function, highlighting potential risks for transplant recipients.
Area of Science:
- Nephrology
- Cardiology
- Transplantation Medicine
Background:
- Cardiac interventions are common in renal transplant recipients due to coronary artery disease.
- The impact of post-transplant cardiac procedures on renal function remains an area of investigation.
Purpose of the Study:
- To evaluate the effect of post-transplant cardiac interventions on renal function in kidney transplant recipients.
- To compare the impact of different cardiac revascularization strategies on kidney function.
Main Methods:
- Retrospective analysis of renal transplant recipients undergoing cardiac procedures between 1997 and 2020.
- Assessment of post-transplant renal function using Glomerular Filtration Rate (GFR) at 6-12 months.
- Comparison of GFR changes between patients who underwent coronary artery bypass grafting (CABG), stenting, or no cardiac intervention.
Main Results:
- Out of 108 patients, 37 underwent stenting and 26 underwent CABG.
- Patients receiving cardiac interventions showed a significant decrease in GFR compared to baseline post-transplant levels.
- No significant GFR decline was observed in patients who did not undergo cardiac intervention.
Conclusions:
- Invasive cardiac revascularization procedures negatively affect post-transplant renal function.
- While interventions were survived, the decline in GFR suggests potential risks.
- The short follow-up period may have influenced the observed outcomes.
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