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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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A New Approach to Quantify and Grade Radiation Dermatitis Using Deep-Learning Segmentation in Skin Photographs.

Y I Park1, S H Choi2, C-S Hong3

  • 1Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, South Korea; Medical Physics and Biomedical Engineering Lab (MPBEL), Yonsei University College of Medicine, Seoul, South Korea.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|August 2, 2022
PubMed
Summary
This summary is machine-generated.

A novel convolutional neural network (CNN) system accurately segments radiation dermatitis from skin photographs and dose data. This tool aids in objective grading and analyzing correlations between radiation dose and dermatitis severity.

Keywords:
Convolutional neural networksdermatitis grading scaleradiation dermatitisradiation therapyskin toxicityskin-dose distribution

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Area of Science:

  • Medical Imaging
  • Radiotherapy Oncology
  • Artificial Intelligence in Medicine

Background:

  • Objective evaluation of radiation dermatitis is crucial for clinical practice and research.
  • Current methods may lack consistency in assessing dermatitis severity and its correlation with radiation dose distribution.

Purpose of the Study:

  • To develop and evaluate a novel radiation dermatitis segmentation system using convolutional neural networks (CNNs).
  • To enable consistent and objective evaluation of radiation dermatitis severity and patterns.

Main Methods:

  • Developed a CNN architecture with dilated convolution and skip connections for segmentation.
  • Trained the network using skin photographs and skin-dose distribution data from 73 radiotherapy patients.
  • Input data combinations included RGB, RGB+CIELAB, and RGB+CIELAB+skin-dose distribution (RGBLAB_D).
  • Evaluated performance using Dice Similarity Coefficient (DSC), sensitivity, specificity, and normalized Matthews Correlation Coefficient (nMCC).

Main Results:

  • The RGBLAB_D input combination demonstrated optimal performance in segmenting radiation dermatitis.
  • Achieved average DSC of 0.62 for faint and 0.69 for severe dermatitis.
  • Reported average sensitivity of 0.61 (faint) and 0.78 (severe), specificity of 0.91 (faint) and 0.96 (severe), and nMCC of 0.77 (faint) and 0.83 (severe).

Conclusions:

  • CNN-based segmentation of radiation dermatitis from skin photographs is feasible and effective.
  • The system can objectively describe radiation dermatitis severity and patterns.
  • This approach can improve the analysis of correlations between dosimetric factors and dermatitis morphology.