Related Experiment Video
Updated: Sep 2, 2025
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Red cell distribution width levels in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma
Jasiya Bashir1, Danish T Beg1, Arshid A Beigh1
1Department of Ophthalmology, GMC, Srinagar, Jammu and Kashmir, India.
Purpose:
The purpose of this study was to assess the levels of red cell distribution width (RDW) in patients with pseudoexfoliation syndrome (PEX) and pseudoexfoliation glaucoma (PEXG), and to compare their RDW values with healthy controls.
Methods:
40 patients with PEX, 40 with PEXG, and 80 control subjects were enrolled in this study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within one hour of blood collection.
Results:
RDW levels were significantly higher in patients with PEX and PEXG than in controls (P = 0.027 and P < 0.001, respectively). Furthermore, a significant difference was found in RDW values between PEXG and PEX groups (P = 0.016). RDW levels were gradually increased from control group to PEXG group (P < 0.001). Multivariate logistic regression analysis revealed that RDW was independently associated with the presence of PEX/PEXG (odds ratio 1.765, 95% confidence interval (CI) 1.095-2.867, P = 0.013).
Conclusion:
We conclude that RDW may be a useful marker for predicting the presence of PEX and progression to PEXG.
