Acalculous Cholecystitis Secondary to Hepatitis C Infection

Polina Gaisinskaya1, Samantha Sugerik1, Christopher M Gebara1

  • 1Internal Medicine, Florida Atlantic University, Florida, USA.

Cureus
|August 3, 2022
PubMed

Insights

Acute acalculous cholecystitis (AAC), gallbladder inflammation without stones, often occurs in critically ill patients. This case highlights acute-on-chronic hepatitis C infection as a potential cause of AAC.

Area of Science:

  • Gastroenterology and Hepatology
  • Critical Care Medicine

Background:

  • Acute acalculous cholecystitis (AAC) is gallbladder inflammation without gallstones.
  • It typically arises from gallbladder stasis or ischemia, triggering inflammation.
  • AAC is often multifactorial and observed in critically ill patients.

Observation:

  • Risk factors for AAC include trauma, burns, infections, parenteral nutrition, and surgery.
  • This case involves a patient with acute-on-chronic hepatitis C infection.
  • The hepatitis C infection was identified as the precipitating factor for AAC.

Findings:

  • The patient presented with symptoms indicative of AAC.
  • Diagnostic evaluation confirmed gallbladder inflammation without gallstones.
  • Hepatitis C infection was identified as the underlying cause.

Implications:

  • Hepatitis C infection should be considered in the differential diagnosis of AAC, especially in patients with risk factors.
  • Early recognition and management of AAC in hepatitis C patients are crucial.
  • This case expands the understanding of AAC etiology in specific patient populations.

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