Evolving Skin Rash as a Rare Cutaneous Manifestation in a Pediatric Patient With COVID-19 Infection
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Updated: Sep 2, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Kedar Tilak1, Karis Joung2, Milena Apath2
1Pediatrics, The Brooklyn Hospital Center, New York, USA.
Insights
This study highlights a rare case of a child with COVID-19 presenting with a unique, evolving skin rash. This cutaneous finding offers insights into the diverse clinical manifestations of coronavirus disease in pediatric patients.
Area of Science:
- Pediatrics
- Infectious Diseases
- Dermatology
Background:
- Coronavirus disease 2019 (COVID-19) has impacted numerous children globally.
- Clinical presentations of COVID-19 in children vary widely, from asymptomatic cases to multi-organ system involvement.
- Skin manifestations are common in viral illnesses, with rashes being a frequent presentation.
Observation:
- A pediatric patient tested positive for COVID-19.
- The patient presented with a rash on the day of initial symptom onset.
- The cutaneous rash evolved over time in correlation with the progression of the COVID-19 illness.
Findings:
- This case highlights a rare cutaneous finding in a child with COVID-19.
- The evolving rash served as an early indicator of infection and disease progression.
- Documenting such rare presentations is crucial for understanding the full spectrum of COVID-19 in children.
Implications:
- This case underscores the importance of considering dermatological symptoms in the diagnosis of COVID-19 in pediatric populations.
- Recognizing diverse cutaneous manifestations can aid in early identification and management of COVID-19 in children.
- Further research into the relationship between COVID-19 and specific skin presentations in children is warranted.
Abstract:
COVID-19 has been one of the common infections that have affected numerous children across the world in the last two years. The clinical manifestations of this virus are varied, ranging from being asymptomatic to affecting multiple organ systems. There is a lot of ongoing research to find out the different manifestations that this infection can have in both adults and children. As with any viral illness, skin is one of the most commonly affected organs, and many viral illnesses can present with a rash. In our case, we found it interesting that our patient who tested positive for COVID-19 had a rash that began on the day of her initial presentation and evolved over time as the disease progressed, and hence, we thought it was important to highlight this rare case presentation as a cutaneous finding in children with COVID-19 infection.
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