Related Experiment Video
Updated: Sep 2, 2025
08:13
Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
974
Endometriosis and cardiovascular disease
Benjamin Marchandot1, Anais Curtiaud1, Kensuke Matsushita1,2
1Division of Cardiovascular Medicine, Nouvel Hopital Civil, Strasbourg University Hospital, 1 place de l'Hôpital, 67000 Strasbourg, France.
European Heart Journal Open
|August 3, 2022
Summary
Endometriosis, a systemic inflammatory disease, is closely linked to cardiovascular disease (CVD) risk. Further research is crucial to understand this connection for better diagnosis and prevention in women.
Area of Science:
- Gynecology
- Cardiology
- Systemic Inflammatory Diseases
Background:
- Endometriosis affects 1 in 10 women of reproductive age.
- It is a complex, hormonal, inflammatory, and systemic condition with significant burdens.
- The interaction between endometriosis and the cardiovascular system is an emerging area of research.
Purpose of the Study:
- To review the pathophysiology of endometriosis, including systemic processes.
- To present clinical evidence on the interaction between endometriosis, cardiovascular risk factors, and cardiovascular disease (CVD).
- To highlight the clinical significance of understanding the endometriosis-cardiovascular interaction.
Main Methods:
- Review of fundamental and clinical evidence.
- Analysis of systemic hormonal, pro-inflammatory, pro-angiogenic, immunologic, and genetic processes in endometriosis.
- Examination of observational studies on endometriosis and CVD associations.
Main Results:
- Accumulating evidence suggests a close relationship between endometriosis and the cardiovascular system.
- Observational studies show small associations between endometriosis and CVD, limited by confounding factors.
- Cardiovascular disease in women with endometriosis is understudied, under-recognized, and underdiagnosed.
Conclusions:
- A strong link exists between endometriosis and cardiovascular health.
- More research is needed to elucidate the pathophysiology, clinical relevance, early diagnosis, and prevention strategies.
- Investigating the cardiovascular-endometriosis interaction is clinically significant for women's health.
More Related Videos
07:12A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice
Published on: November 24, 2020
5.4K
07:20Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
Published on: December 21, 2012
16.0K
Related Concept Videos
01:27Psychoneuroimmunology: Cardiovascular Disease
71
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
71
02:07Oogenesis
64.2K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
64.2K
01:30Coronary Artery Disease I: Introduction
50
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
50
01:24Disorders of the Female Reproductive System
475
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
475
01:22Mitral Stenosis I: Introduction
30
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
30
01:25Cardiomyopathy I: Introduction and Classification
47
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
47