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Updated: Sep 2, 2025
Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
Published on: March 3, 2023
[Results of redo liver resections for metastatic colorectal cancer]
O I Kit1, Yu A Gevorkyan1, N V Soldatkina1
1National Medical Research Centre for Oncology, Rostov-on-Don, Russia.
Objective:
To analyze patients undergoing redo liver resections for metastatic colorectal cancer.
Material And Methods:
The study included 14 patients with colorectal cancer who underwent several redo liver resections for metastatic lesions between September 2011 and June 2021. Mean age of patients was 63.5 years. Left-sided colonic G2 adenocarcinoma T4N1-2 prevailed (wild-type KRAS).
Results:
Fourteen patients (100%) underwent two liver resections, 7 (50%) - three resections, 1 (7.1%) - four resections. Mean period between the first and the second liver resections was 16.2 months, between the second and the third resections - 9.9 months, between the third and the fourth resections - 5 months. Maximum follow-up period after primary surgery was 9 years and 9 months. Seventy-five percent of patients were alive after 34.2 months, 50% - after 58.9 months. N+ status of colorectal tumor decreased survival while KRAS mutation and synchronous metastatic liver lesions increased survival.
Conclusion:
Redo liver resections for metastatic colorectal cancer are safe and ensure favorable long-term survival in certain patients.
