Related Experiment Video
Updated: Sep 2, 2025
13:25
Transient Transduction of the Strobilated Forms of Echinococcus granulosus
Published on: September 16, 2022
3.1K
[Liver echinococcosis in a non-endemic region]
L P Kotelnikova1,2, G Yu Mokina2, A N Fedachuk2
1Vagner Perm State Medical University, Perm, Russia.
Khirurgiia
|August 3, 2022
Summary
Diagnosing liver echinococcosis in non-endemic areas is challenging, with final diagnoses often made during surgery. However, surgical treatment leads to a favorable long-term quality of life for patients.
Area of Science:
- Medicine
- Parasitology
- Surgery
Background:
- Liver echinococcosis is a parasitic infection caused by Echinococcus granulosus.
- Diagnosis and treatment can be challenging, especially in non-endemic regions.
Purpose of the Study:
- To investigate the clinical features and diagnostic challenges of liver echinococcosis in a non-endemic region.
- To evaluate the long-term outcomes and quality of life following surgical interventions.
Main Methods:
- Retrospective analysis of 36 patients with liver echinococcosis operated on in a non-endemic region over 15 years.
- Utilized enzyme immunoassay for antibody detection, ultrasound and CT for diagnosis, and the SF-36 questionnaire for quality of life assessment.
Main Results:
- Complicated liver echinococcosis was observed in 36% of patients; diagnosis was confirmed intraoperatively in 8.33% of cases.
- CT demonstrated the highest diagnostic sensitivity (91.7%). Surgical interventions included echinococcectomy, pericystectomy, and liver resection.
- Long-term recurrence occurred in 11.1% of cases. Patients reported a favorable quality of life, with physical health scores slightly exceeding mental health scores.
Conclusions:
- Liver echinococcosis diagnosis in non-endemic regions presents significant challenges, often requiring intraoperative confirmation.
- Surgical management is effective in achieving favorable long-term quality of life for patients with liver echinococcosis.
Related Concept Videos
01:26Diseases of the Liver and Gallbladder
933
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
933
01:25Ultrasound II: Endoscopic Ultrasound and FibroScan
191
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
191
01:17Hepatic Drug Excretion: Enterohepatic Cycling
1.7K
Enterohepatic cycling involves the active secretion of drugs and their metabolites into the bile via transporters in the canalicular membrane of hepatocytes. This secretion is an integral part of the digestive process, releasing these substances into the gastrointestinal (GI) tract.
Post-release drugs and metabolites can be reabsorbed into the body from the intestine. For conjugated metabolites like glucuronides, reabsorption requires enzymatic hydrolysis by intestinal microflora. This...
Post-release drugs and metabolites can be reabsorbed into the body from the intestine. For conjugated metabolites like glucuronides, reabsorption requires enzymatic hydrolysis by intestinal microflora. This...
1.7K