Related Experiment Video

Updated: Sep 2, 2025

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

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Surgical considerations in cystic fibrosis: what every general surgeon needs to know

John D Chetwood1,2, Anastasia Volovets1,2, Sheila Sivam3

  • 1AW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

ANZ Journal of Surgery
|August 3, 2022
PubMed

Insights

Cystic fibrosis (CF) patients are living longer and facing new surgical challenges. This review updates general surgeons on managing CF-related gastrointestinal conditions in these complex patients.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pulmonology

Background:

  • Cystic fibrosis (CF) is a multisystem disorder impacting the gastrointestinal tract.
  • Improved therapies increase CF patient lifespan to ~50 years.
  • Longer lifespans lead to increased surgical comorbidities in CF patients.

Purpose of the Study:

  • To provide general surgeons with an update on surgical issues in cystic fibrosis patients.
  • To highlight the unique challenges in managing CF patients with surgical conditions.
  • To prepare surgeons for multidisciplinary care of complex CF patients.

Main Methods:

  • This is a review article.
  • It synthesizes current knowledge on CF-related surgical conditions.
  • Focuses on gastrointestinal manifestations and management.

Main Results:

  • CF patients present with surgical issues like distal intestinal obstruction syndrome and colorectal cancer.
  • Management requires understanding CF-specific challenges: immunosuppression, respiratory compromise, multi-organ dysfunction.
  • Surgical care for CF patients is evolving.

Conclusions:

  • General surgeons will increasingly manage CF patients with surgical conditions.
  • A thorough understanding of CF pathophysiology is crucial for effective surgical care.
  • Multidisciplinary team involvement is essential for optimal outcomes in CF surgical patients.

Keywords:
colorectal carcinomacystic fibrosisdistal intestinal obstruction syndromeintussusceptionpancreatitis

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