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Updated: Sep 2, 2025

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury
Published on: September 7, 2018
Carotid free-floating thrombus during COVID-19 vaccine era: causality or not?
Ludovica Ferraù1, Masina Cotroneo1, Cristina Dell'Aera1
1Stroke Unit, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Abstract:
Carotid free-floating thrombus (FFT) is very rarely diagnosed in patients with acute ischemic stroke. It is a real clinical emergency due to the significant risk of death associated with thromboembolic complications. Herein, we present three patients with ischemic stroke caused by carotid FFT after less than 20 days from administration of mRNA vaccine BNT162b1 (Pfizer/BioNTech) for Severe Acute Respiratory Syndrome-CoronaVirus 2 (SARS-CoV-2). To our knowledge, these are the first cases reporting carotid FTT following SARS-CoV-2 vaccination.
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