Related Experiment Video
Updated: Sep 2, 2025

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
Published on: April 7, 2015
Case Report: Cardiac Multiple Thrombus and Pulmonary Embolism Associated With Mycoplasma Pneumonia Infection in a
Tongqiang Zhang1, Jiafeng Zheng1, Hongbo Wang1
1Department of Respiratory, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, China.
Abstract:
Mycoplasma pneumoniae (MP) is a common pathogen of lower respiratory tract infection in children and adolescents. Some patients with MP infection are self-limiting, while with the increase of severe or refractory Mycoplasma pneumoniae pneumonia (MPP) in recent years, there is a great increase in reports of thromboembolism in multiple organs, including lung, brain, spleen, and peripheral arteries. Cardiac multiple thrombi and pulmonary embolism associated with MP infection have not been reported. The most effective treatment option for cardiac thrombus was surgical resection for fear of thrombus detachment and causing new thromboembolism. Herein, we present a patient with cardiac multiple thrombi and pulmonary embolism in MPP for the first time. In our case, the child recovered after conservative medical treatment, which provides a therapeutic option for children with cardiac multiple thrombi.
Insights
Mycoplasma pneumoniae pneumonia can cause serious cardiac thrombi and pulmonary embolism. A child with this condition recovered with conservative medical treatment, offering a new therapeutic option.
Area of Science:
- Pediatrics
- Infectious Diseases
- Cardiology
Background:
- Mycoplasma pneumoniae (MP) commonly causes respiratory infections in children.
- Severe or refractory Mycoplasma pneumoniae pneumonia (MPP) is increasingly associated with thromboembolism in various organs.
- Cardiac thrombi and pulmonary embolism linked to MP infection have not been previously reported.
Observation:
- A pediatric case of severe Mycoplasma pneumoniae pneumonia (MPP) presented with cardiac multiple thrombi and pulmonary embolism.
- The patient exhibited symptoms indicative of widespread thromboembolic events originating from the heart.
Findings:
- This is the first reported case of cardiac multiple thrombi and pulmonary embolism occurring in conjunction with Mycoplasma pneumoniae pneumonia (MPP).
- The child successfully recovered following conservative medical management, challenging the assumption that surgical resection is the only effective treatment for cardiac thrombus in this context.
Implications:
- Conservative medical treatment may be a viable therapeutic option for pediatric patients with cardiac multiple thrombi associated with Mycoplasma pneumoniae pneumonia (MPP).
- This case expands the understanding of potential complications of Mycoplasma pneumoniae infections and highlights the importance of considering thromboembolic events.
- Further research is warranted to explore the efficacy and safety of conservative management strategies for cardiac thrombi in pediatric MPP cases.
More Related Videos
06:04Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
11:32Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Related Concept Videos
Pneumonia III: Complications and Assessment
Pneumonia II: Pathophysiology
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism I: Introduction
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories: