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[Monkeypox].

G Absil1, L Sougne2, D Lahrichi1

  • 1Service de Dermatologie, CHU Liège, Belgique.

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|August 4, 2022
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Summary
This summary is machine-generated.

Monkeypox (MPX) is a rare zoonotic disease typically found in Africa, but outbreaks now occur globally. Diagnosis involves PCR detection of the MPX virus, with supportive care for management as specific treatments are unavailable.

Keywords:
InfectionOrthopoxvirusOutbreakZoonotic diseaseMonkeypox

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Virology

Background:

  • Monkeypox (MPX) is a rare zoonotic disease endemic to Central and West Africa.
  • Recent years have seen an increase in MPX outbreaks outside of its endemic regions.

Observation:

  • MPX typically presents with flu-like symptoms, swollen lymph nodes, and a characteristic rash.
  • Transmission occurs through direct or indirect contact with infected animals or, less commonly, humans.

Findings:

  • The gold standard for MPX diagnosis is the detection of the MPX virus (MPXV) via PCR on skin lesion fluid.
  • The disease usually resolves within 2-5 weeks, but complications and sequelae can occur.

Implications:

  • Current management for MPX is primarily supportive, focusing on symptom relief and complication management.
  • The increasing global spread highlights the need for enhanced surveillance and public health strategies for MPX.
  • Further research into specific antiviral treatments for MPX may be warranted given the potential for severe outcomes.