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Updated: Sep 2, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
[Pulmonary manifestations in long COVID]
Natascha Sommer1, Bernd Schmeck2,3
1Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Justus-Liebig-Universität, Klinikstr. 33, 35390, Gießen, Deutschland. natascha.sommer@innere.med.uni-giessen.de.
Pulmonary issues are common after SARS-CoV-2 infection, leading to long COVID syndrome. While symptoms and lung changes often improve, some patients need ongoing management for persistent respiratory problems.
Area of Science:
- Pulmonology
- Infectious Diseases
- Post-COVID Conditions
Background:
- Pulmonary manifestations are frequent complications following severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infections.
- These respiratory issues are commonly grouped under the umbrella term long COVID syndrome.
Purpose of the Study:
- To provide a comprehensive summary of the existing scientific literature concerning pulmonary manifestations in long COVID.
- To highlight expert opinions and current recommendations for managing these conditions.
Main Methods:
- Literature review focusing on pulmonary sequelae of SARS-CoV-2 infection.
- Inclusion of expert opinions and clinical recommendations.
- Analysis of diagnostic approaches and therapeutic strategies.
Main Results:
- Dyspnea is the most prevalent symptom in long COVID patients, following chronic fatigue.
- Radiological changes, interstitial lung disease characteristics, restrictive ventilation patterns, and diffusion capacity limitations are common findings, particularly after severe COVID-19.
- While pulmonary abnormalities tend to improve, some patients experience persistent issues months post-infection, with the exact causes and contributing factors remaining under investigation.
Conclusions:
- Knowledge regarding pulmonary manifestations in long COVID is continually evolving.
- A significant limitation exists due to the scarcity of clinical trials, precluding the development of evidence-based guidelines for diagnosis and therapy.
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