Valence Bond Theory
Crystal Field Theory - Tetrahedral and Square Planar Complexes
Properties of Organometallic Compounds
Complexation Equilibria: The Chelate Effect
Crystal Field Theory - Octahedral Complexes
Metal-Ligand Bonds
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Lorenzo Arnal1, Daniel Escudero2, Sara Fuertes1
1Departamento de Química Inorgánica, Facultad de Ciencias, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC - Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain.
Platinum complexes undergo double oxidative addition with alkyl halides via an SN2 pathway. This study elucidates the reaction mechanisms and characterizes novel platinum(III) and platinum(IV) intermediates, providing insights into high-valent platinum chemistry.
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