Intraoperative radiotherapy (IORT) offers a potent single dose of electrons for challenging cancers. This advanced technique is increasingly adopted worldwide for various advanced and recurrent malignancies.
Area of Science:
Oncology
Radiation Oncology
Surgical Oncology
Context:
Intraoperative radiotherapy (IORT) is a specialized technique delivering high-dose radiation during surgery.
It addresses locally advanced or difficult-to-treat malignancies often resistant to conventional external beam radiotherapy.
The global adoption of IORT is rising due to improved medical accelerator availability and positive outcomes.
Purpose:
To investigate the application and efficacy of intraoperative radiotherapy for various cancers.
To highlight the suitability of IORT for malignancies adjacent to normal tissues or organs with low tolerance doses.
To expand the understanding of IORT's role in treating recurrent or complex tumors.
Summary:
IORT involves administering a large, single dose of electrons directly to a tumor during surgery.
It is indicated for cancers of the stomach, liver, pancreas, colorectum, bladder, prostate, and uterus.
Recurrent or challenging tumors in the brain, lung, mediastinum, bone, and soft tissues are also candidates for IORT.
Impact:
IORT provides a valuable therapeutic option for complex oncological cases.
It allows for precise radiation delivery, potentially sparing surrounding healthy tissues.
The expanding use of IORT signifies its growing importance in multidisciplinary cancer treatment strategies.