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[Combination chemotherapy including cis-platinum in Ewing's sarcoma]
Gan to Kagaku Ryoho. Cancer & Chemotherapy
|June 1, 1987
Summary
Cis-platinum showed effectiveness in treating Ewing's sarcoma. Preoperative administration in 5 patients led to good imaging responses with manageable side effects like hearing loss and mild bone marrow suppression.
Area of Science:
- Pediatric Oncology
- Medical Imaging
- Pharmacology
Background:
- Ewing's sarcoma is a rare bone and soft tissue cancer primarily affecting children and young adults.
- Effective preoperative (neoadjuvant) treatment is crucial for improving outcomes in Ewing's sarcoma.
- Cis-platinum is a platinum-based chemotherapy agent with known efficacy in various solid tumors.