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Equisetum hyemale-derived unprecedented bioactive composite for hard and soft tissues engineering
Rosangela Maria Ferreira da Costa E Silva1, Ivana Márcia Alves Diniz2, Natália Aparecida Gomes2
1Universidade Federal da Fronteira Sul, Campus Realeza-PR, Realeza, Paraná, 85770-000, Brazil. rosangela_ferreirafeliz@yahoo.com.br.
Scientific Reports
|August 4, 2022
Summary
Researchers developed a novel bioactive composite (BG-Carb) from plant waste, avoiding toxic reagents and high temperatures. This sustainable material shows potential for tissue engineering applications.
Area of Science:
- Biomaterials Science
- Materials Chemistry
- Tissue Engineering
Background:
- Traditional bioactive glasses (BGs) synthesis involves toxic reagents and high temperatures.
- Optimizing BG preparation while minimizing environmental impact is crucial.
Purpose of the Study:
- To develop a sustainable bioactive composite (BG-Carb) from Equisetum hyemale plant ashes.
- To overcome drawbacks of conventional bioactive glass synthesis.
Main Methods:
- Treatment of plant ashes in an ethanol/water solution.
- Characterization using SEM, TEM, ICP-OES, BET, FTIR, and XRD.
- In vitro assessment of biocompatibility and osteo-differentiation capacity on MC3T3-E1 cells.
Main Results:
- A bioactive composite (BG-Carb) with a surface area of 121 m² g⁻¹ was successfully synthesized.
- Formation of a hydroxyapatite (HA) surface layer was confirmed in vitro and enhanced after SBF immersion.
- BG-Carb exhibited no cytotoxicity and comparable osteo-differentiation capacity to the positive control.
Conclusions:
- The plant waste-derived BG-Carb is a promising, eco-friendly material for hard and soft tissue engineering.
- This approach offers a sustainable alternative to conventional bioactive glass production.
