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Published on: December 15, 2010
The Fractal Viewpoint of Tumors and Nanoparticles
Athanasios Alexiou1,2, Christos Tsagkaris1,3, Stylianos Chatzichronis1
1Department of Science and Engineering, Novel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.
Abstract:
Even though the promising therapies against cancer are rapidly improved, the oncology patients population has seen exponential growth, placing cancer in 5th place among the ten deadliest diseases. Efficient drug delivery systems must overcome multiple barriers and maximize drug delivery to the target tumors, simultaneously limiting side effects. Since the first observation of the quantum tunneling phenomenon, many multidisciplinary studies have offered quantum-inspired solutions to optimized tumor mapping and efficient nanodrug design. The property of a wave function to propagate through a potential barrier offer the capability of obtaining 3D surface profiles using imaging of individual atoms on the surface of a material. The application of quantum tunneling on a scanning tunneling microscope offers an exact surface roughness mapping of tumors and pharmaceutical particles. Critical elements to cancer nanotherapeutics apply the fractal theory and calculate the fractal dimension for efficient tumor surface imaging at the atomic level. This review study presents the latest biological approaches to cancer management based on fractal geometry.
Insights
Quantum tunneling and fractal geometry offer advanced cancer nanotherapeutics. These methods enable precise tumor mapping and nanodrug design for improved oncology patient outcomes.
Area of Science:
- Quantum physics applications in medicine
- Nanotechnology in drug delivery
- Fractal geometry in biological imaging
Background:
- Cancer remains a leading cause of death, necessitating improved drug delivery systems.
- Existing therapies face challenges in targeting tumors and minimizing side effects.
- Nanotherapeutics require precise tumor mapping and efficient drug design.
Approach:
- Utilizing quantum tunneling phenomenon for atomic-level surface imaging.
- Applying scanning tunneling microscopy for detailed surface roughness mapping of tumors and nanoparticles.
- Integrating fractal theory and fractal dimension calculations for enhanced tumor imaging.
Key Points:
- Quantum tunneling enables 3D surface profiling at the atomic scale.
- Scanning tunneling microscopy provides exact surface roughness data for tumors and drug particles.
- Fractal geometry is crucial for efficient atomic-level tumor surface analysis in nanotherapeutics.
Conclusions:
- Fractal geometry-based approaches represent the latest advancements in cancer nanotherapeutics.
- This review highlights biological strategies for cancer management leveraging fractal geometry.
- Quantum-inspired imaging and fractal analysis are key to optimizing nanodrug delivery and efficacy.
