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Mucocutaneous Leishmaniasis in a Pregnant Immigrant
Neima Briggs1, Brian M Wei2, Chaarushi Ahuja2
1Section of Infectious Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Open Forum Infectious Diseases
|August 5, 2022
Summary
Cutaneous leishmaniasis in pregnancy poses risks, but liposomal amphotericin B offers a safe and effective treatment option. This case study highlights a favorable maternal and fetal outcome with this therapy.
Area of Science:
- Parasitic infections
- Maternal-fetal medicine
- Dermatology
Background:
- Cutaneous leishmaniasis (CL) during pregnancy presents significant risks, including maternal morbidity and potential fetal mortality.
- Limited therapeutic choices exist for pregnant individuals with CL.
- Mucocutaneous leishmaniasis can manifest with severe, widespread lesions.
Purpose of the Study:
- To report a case of successful treatment of cutaneous leishmaniasis in a pregnant patient.
- To evaluate the safety and efficacy of liposomal amphotericin B in this specific patient population.
- To underscore the importance of available therapeutic options for pregnant women with CL.
Main Methods:
- A case report detailing the clinical presentation and treatment of a pregnant immigrant with extensive mucocutaneous leishmaniasis.
- Administration of liposomal amphotericin B as the primary therapeutic intervention.
- Monitoring of clinical response and maternal-fetal well-being throughout treatment.
Main Results:
- The patient presented with exuberant mucocutaneous leishmaniasis lesions.
- Liposomal amphotericin B treatment resulted in a favorable clinical response.
- No adverse effects were observed in the mother or fetus during the treatment course.
Conclusions:
- Liposomal amphotericin B is a viable and effective treatment for cutaneous leishmaniasis in pregnant women.
- Prompt diagnosis and treatment are crucial for managing CL during pregnancy.
- This case supports the use of liposomal amphotericin B to improve maternal and fetal outcomes in CL.
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