[Design and Verification of Lung Diffusion Function Detection System].

Area of Science:

• Pulmonary Medicine
• Medical Device Engineering
• Respiratory Physiology

Background:

• Accurate assessment of lung diffusion function is crucial for diagnosing and managing respiratory diseases.
• Existing methods may have limitations in terms of accuracy, cost, or accessibility.
• Chronic Obstructive Pulmonary Disease (COPD) diagnosis relies heavily on pulmonary function tests.

Purpose of the Study:

• To design and develop a novel system for quantitative detection and evaluation of lung diffusion function.
• To accurately measure pulmonary diffusing capacity for carbon monoxide (D_lCO) and alveolar volume.
• To validate the system's accuracy for potential use in early COPD screening.

Main Methods:

• The system utilizes the single-breath method for lung function measurement.
• It incorporates controllable collection of air, test gas, and calibration gas sources.
• Non-dispersive infrared sensors, differential pressure sensors, and environmental sensors (temperature, humidity, atmospheric pressure) are employed for data acquisition.

Main Results:

• The system successfully calculated pulmonary diffusing capacity for carbon monoxide (D_lCO) and alveolar volume.
• Preliminary verification demonstrated high accuracy, with errors not exceeding 5% for D_lCO and alveolar volume.
• The system provides quantitative detection and evaluation of lung diffusion capacity.

Conclusions:

• The developed lung diffusion function detection system exhibits high accuracy and reliability.
• Its precision makes it a valuable tool for the early screening and accurate assessment of COPD.
• The system's design offers a promising approach for improved respiratory diagnostics.