Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Analyte Adsorption and Distribution01:09

Analyte Adsorption and Distribution

800
In certain chromatographic separations, solutes transfer between the mobile phase and the stationary phase via sorption, which typically refers to the process of adsorption. For many chromatographic systems, the sorption process often depends on the polarity of the compounds—an expression of the overall dipole moment within the molecule. During the separation process, there is competition between the solute and solvent for adsorption to the stationary phase. Highly polar compounds and...
800
Silica Gel Column Chromatography: Overview01:10

Silica Gel Column Chromatography: Overview

1.6K
Silica gel column chromatography is a technique for separating compounds using a column packed with silica gel as the stationary phase. This method relies on differences in the polarity of compounds. Based on their polarities, compounds move between the stationary phase (silica gel) and the mobile phase (the solvent), forming discrete bands in the column.
Polar components tend to bind strongly to the silica gel, causing them to move slowly through the column. In contrast, nonpolar compounds...
1.6K
Size-Exclusion Chromatography01:08

Size-Exclusion Chromatography

742
In size-exclusion chromatography (SEC), also known as molecular-exclusion or gel-permeation chromatography, molecules are separated based on their sizes. This technique is important for separating large molecules such as polymers and biomolecules. The two classes of micron-sized stationary phases encountered in SEC are silica particles and cross-linked polymer resin beads. Both materials are porous, but their pore sizes vary significantly.
Silica particles offer advantages such as rigidity,...
742
Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

35.5K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
35.5K
Extraction: Partition and Distribution Coefficients01:14

Extraction: Partition and Distribution Coefficients

2.8K
The distribution law or Nernst's distribution law is the law that governs the distribution of a solute between two immiscible solvents. This law, also known as the partition law, states that if a solute is added to the mixture of two immiscible solvents at a constant temperature, the solute is distributed between the two solvents in such a way that the ratio of solute concentrations in the solvents remains constant at equilibrium.
For extracting a solute from an aqueous phase into an...
2.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Uncovering the linear boron environment in Na<sub>3</sub>BP<sub>2</sub> through solid-state <sup>11</sup>B NMR spectroscopy.

Physical chemistry chemical physics : PCCP·2026
Same journal

Detuning and the excitation delay in photo-stimulated vibrational state transitions in HF under the classical field approximation.

Physical chemistry chemical physics : PCCP·2026
Same journal

Diagnosing conformational preferences of lower-rim-functionalized thiophene resorcin[4]arenes and pyrogallol[4]arenes for predictable supramolecular assembly design.

Physical chemistry chemical physics : PCCP·2026
Same journal

Revealing Griffithsin recognition of diverse virus-associated <i>N</i>-glycans using atomistic simulations: glycan compositions and branching patterns as key molecular determinants.

Physical chemistry chemical physics : PCCP·2026
Same journal

Electron nuclear dynamics of H<sup>+</sup> + uracil at <i>E</i><sub>Lab</sub> = 1.47 and 4.00 keV: a prototype of ion cancer therapy reactions.

Physical chemistry chemical physics : PCCP·2026
Same journal

Wetting-state-dependent desorption of molten Al droplets from striped SiC surfaces under vertical harmonic vibration.

Physical chemistry chemical physics : PCCP·2026

Related Experiment Video

Updated: Sep 2, 2025

Author Spotlight: Characterizing Porous Materials for Aiding the Development of Robust Metal-Organic Frameworks with Adsorption Behavior
06:45

Author Spotlight: Characterizing Porous Materials for Aiding the Development of Robust Metal-Organic Frameworks with Adsorption Behavior

Published on: March 8, 2024

8.0K

General cluster sorption isotherm: surface area determination.

Christoph Buttersack1

  • 1Institute of Chemical Technology, Leipzig University, Linnéstr. 3, 04103 Leipzig, Germany. christoph.buttersack@uni-leipzig.de.

Physical Chemistry Chemical Physics : PCCP
|August 5, 2022
PubMed
Summary

A modified General Cluster Sorption Isotherm (GCSI) method accurately determines monolayer coverage and surface area. This advanced GCSI approach refines previous methods, offering a more precise alternative to BET for gas sorption analysis.

More Related Videos

Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices
09:31

Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices

Published on: March 27, 2019

9.6K
Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry
07:53

Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry

Published on: March 1, 2020

7.4K

Related Experiment Videos

Last Updated: Sep 2, 2025

Author Spotlight: Characterizing Porous Materials for Aiding the Development of Robust Metal-Organic Frameworks with Adsorption Behavior
06:45

Author Spotlight: Characterizing Porous Materials for Aiding the Development of Robust Metal-Organic Frameworks with Adsorption Behavior

Published on: March 8, 2024

8.0K
Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices
09:31

Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices

Published on: March 27, 2019

9.6K
Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry
07:53

Analysis of Complex Molecules and Their Reactions on Surfaces by Means of Cluster-Induced Desorption/Ionization Mass Spectrometry

Published on: March 1, 2020

7.4K

Area of Science:

  • Physical Chemistry
  • Surface Science
  • Materials Science

Background:

  • The General Cluster Sorption Isotherm (GCSI) is a theoretical framework for understanding gas sorption on surfaces.
  • Accurate determination of monolayer coverage and surface area is crucial for characterizing porous materials.

Purpose of the Study:

  • To modify the GCSI by separating lateral and vertical forces to identify monolayer coverage.
  • To compare the modified GCSI method with existing techniques like BET and ESW for surface area determination.

Main Methods:

  • Modification of the GCSI by analyzing the ratio of adsorption contributions in vertical and lateral directions.
  • Application of the modified GCSI to experimental type II sorption isotherms.
  • Comparison of surface area results with BET and Excess Surface Work (ESW) methods.

Main Results:

  • An inflection point in the adsorption ratio reliably indicates monolayer coverage.
  • The modified GCSI method provides accurate surface area values, especially when BET overestimates.
  • The GCSI method encompasses the BET method as a special case under strong sorbate-surface interactions.

Conclusions:

  • The modified GCSI offers a robust method for determining monolayer coverage and surface area from sorption isotherms.
  • This approach provides a more accurate assessment of surface area compared to BET for certain gas-surface systems.
  • Sufficiently broad experimental data is essential for reliable application of the modified GCSI.