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Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
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Mechanically active small intestinal submucosa hydrogel for accelerating chronic wound healing
Xiao-Ya Chen1, Yi Wang2,3, Shi-Qing Ma4
1College of Bioengineering and Technology, Tianjin Medical University, Tianjin, 300070, China.
Journal of Materials Chemistry. B
|August 5, 2022
Abstract:
The treatment of chronic wounds is still a challenge worldwide. Here, inspired by mechanically induced embryonic wound healing, we design a mechanically active small intestinal submucosa based hydrogel (SIS-PNIPAm). The mechanical activity, biocompatibility, and bioactivity (angiogenesis and immunoregulation) of the SIS-PNIPAm hydrogel enable the fast healing of diabetic rat full-thickness wounds.

