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Updated: Sep 2, 2025

Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model
Published on: July 28, 2023
A Review of the Diagnosis and Treatment of Necrotizing Enterocolitis
Xue Cai1, Heather L Liebe2, Alena Golubkova2
1Department of Surgery, The University of Oklahoma Health Sciences Center, 800 Research Parkway Suite 449, Oklahoma City, OK 73104, Japan.
Abstract:
Necrotizing enterocolitis (NEC) is a devastating disease that primarily affects the gastrointestinal tract of premature neonates. The diagnosis and treatment of NEC remain challenging. New biomarkers and potential treatments for NEC have emerged in recent years, leading to the potential of earlier therapeutic intervention and improved outcomes. This paper aims to provide a review of the most recent diagnostic indicators and therapeutics of NEC along with a brief overview of future directions of research into this disease.
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