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S2k guideline: Rosacea.

Benjamin M Clanner-Engelshofen1, Dominik Bernhard1, Sonja Dargatz2

  • 1Department and Clinic for Dermatology and Allergology, University Hospital Munich, LMU Munich, Germany.

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|August 5, 2022
PubMed
Summary
This summary is machine-generated.

This S2k guideline updates rosacea diagnosis and treatment. Key recommendations include trigger avoidance, topical therapies like metronidazole and azelaic acid, and systemic options for severe cases.

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Area of Science:

  • Dermatology
  • Clinical Guidelines

Background:

  • Rosacea is a common chronic inflammatory skin condition primarily affecting the face.
  • It presents with erythema, telangiectasia, flushing, and inflammatory papulopustules, potentially progressing to severe manifestations like phyma.

Purpose of the Study:

  • To provide an updated and upgraded S2k guideline for the diagnosis and treatment of rosacea.
  • To consolidate recommendations from an interdisciplinary committee representing various medical societies and patient organizations.

Main Methods:

  • Development of an interdisciplinary guideline by a committee including representatives from dermatology, ophthalmology, dermopharmacy, and patient advocacy groups.
  • Review and synthesis of current evidence for rosacea diagnosis and treatment strategies.

Main Results:

  • Recommendations include avoiding trigger factors and using topical treatments such as metronidazole, azelaic acid, or ivermectin.
  • For persistent erythema, topical vasoconstrictors (brimonidine, oxymetazoline) are suggested.
  • Systemic therapy with low-dose doxycycline or isotretinoin is recommended for severe or therapy-resistant papulopustular rosacea.
  • Ocular rosacea management involves lid margin hygiene and topical agents like ciclosporin, azithromycin, ivermectin, or metronidazole.

Conclusions:

  • The guideline offers comprehensive, evidence-based recommendations for managing rosacea across its various presentations.
  • Emphasizes a multidisciplinary approach and tailored treatment strategies based on disease severity and subtype.