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Hemodiafiltration using dialysate as substitution fluid.

B Canaud, Q V Nguyen, A Argiles

    Artificial Organs
    |April 1, 1987
    PubMed
    Summary
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    This study modified a standard hemodialysis machine for cost-effective, in-line substitution fluid production. The new method is safe, simple, and enables high-flux hemodiafiltration (HDF) affordably.

    Area of Science:

    • Nephrology
    • Biomedical Engineering

    Background:

    • High-flux hemodiafiltration (HDF) is effective but costly.
    • Substitution fluid production contributes significantly to HDF expenses.

    Purpose of the Study:

    • To develop a cost-effective method for producing substitution fluid for HDF.
    • To adapt standard hemodialysis equipment for in-line fluid generation.

    Main Methods:

    • Modification of a standard hemodialysis machine.
    • In-line production of substitution fluid using bicarbonate dialysate.
    • Utilizing a hemodiafilter with a small membrane surface area.

    Main Results:

    • The in-line substitution fluid production was bacteriologically safe.

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  • The procedure proved simple to operate.
  • This approach offers a cost-effective way to perform high-flux HDF.

    • Conclusions:

    • Modified hemodialysis machines can safely and affordably produce substitution fluid for HDF.
    • This innovation reduces the financial barriers to high-flux HDF treatment.