Age and ageing cardiovascular collection: blood pressure, coronary heart disease and heart failure

Jane A H Masoli1,2, Ekow Mensah3, Chakravarthi Rajkumar3,4

  • 1Healthcare for Older People, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.

Age and Ageing
|August 7, 2022
PubMed

Insights

Cardiovascular disease risk increases with age. Personalized blood pressure management and understanding orthostatic hypotension are crucial for healthy aging and preventing falls in older adults.

Area of Science:

  • Gerontology
  • Cardiology
  • Public Health

Background:

  • Cardiovascular disease is a leading cause of mortality and morbidity worldwide, with risk escalating with age.
  • Understanding cardiovascular aging is vital for promoting healthy aging and preventing adverse health outcomes.
  • Age-related changes in blood pressure regulation, including orthostatic hypotension, increase fall risk in older adults.

Purpose of the Study:

  • To review key themes in cardiovascular aging, focusing on blood pressure management and orthostatic hypotension.
  • To highlight research needs for understanding blood pressure changes and management in the aging population.
  • To examine differences in inpatient care and outcomes for older adults experiencing heart attacks.

Main Methods:

  • Review of selected papers published in Age and Ageing since 2011.
  • Analysis of UK national audit data on inpatient clinical care of older people with heart attacks.
  • Discussion of the impact of frailty and multimorbidity on cardiovascular disease care and outcomes.

Main Results:

  • Personalized blood pressure management is essential, balancing treatment targets with avoiding overtreatment in vulnerable older individuals.
  • Orthostatic hypotension is common in aging and frailty, predisposing individuals to falls.
  • Older adults (over 80) show improved heart attack survival but receive less specialist cardiology input compared to younger patients, potentially due to complex health conditions.

Conclusions:

  • Individualized, person-centered, and multidisciplinary care is necessary to address the diverse needs of the aging population with cardiovascular disease.
  • Further research is needed to optimize blood pressure management and address orthostatic hypotension in older adults.
  • Clinical care for older adults with cardiovascular events must account for frailty, multimorbidity, and differing presentations.

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