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Age and ageing cardiovascular collection: blood pressure, coronary heart disease and heart failure
Jane A H Masoli1,2, Ekow Mensah3, Chakravarthi Rajkumar3,4
1Healthcare for Older People, Royal Devon University Healthcare NHS Foundation Trust, Exeter, UK.
Insights
Cardiovascular disease risk increases with age. Personalized blood pressure management and understanding orthostatic hypotension are crucial for healthy aging and preventing falls in older adults.
Area of Science:
- Gerontology
- Cardiology
- Public Health
Background:
- Cardiovascular disease is a leading cause of mortality and morbidity worldwide, with risk escalating with age.
- Understanding cardiovascular aging is vital for promoting healthy aging and preventing adverse health outcomes.
- Age-related changes in blood pressure regulation, including orthostatic hypotension, increase fall risk in older adults.
Purpose of the Study:
- To review key themes in cardiovascular aging, focusing on blood pressure management and orthostatic hypotension.
- To highlight research needs for understanding blood pressure changes and management in the aging population.
- To examine differences in inpatient care and outcomes for older adults experiencing heart attacks.
Main Methods:
- Review of selected papers published in Age and Ageing since 2011.
- Analysis of UK national audit data on inpatient clinical care of older people with heart attacks.
- Discussion of the impact of frailty and multimorbidity on cardiovascular disease care and outcomes.
Main Results:
- Personalized blood pressure management is essential, balancing treatment targets with avoiding overtreatment in vulnerable older individuals.
- Orthostatic hypotension is common in aging and frailty, predisposing individuals to falls.
- Older adults (over 80) show improved heart attack survival but receive less specialist cardiology input compared to younger patients, potentially due to complex health conditions.
Conclusions:
- Individualized, person-centered, and multidisciplinary care is necessary to address the diverse needs of the aging population with cardiovascular disease.
- Further research is needed to optimize blood pressure management and address orthostatic hypotension in older adults.
- Clinical care for older adults with cardiovascular events must account for frailty, multimorbidity, and differing presentations.
Abstract:
As people age they are at increased risk of cardiovascular disease, the leading cause of mortality and morbidity worldwide. Understanding cardiovascular ageing is essential to preserving healthy ageing and preventing serious health outcomes. This collection of papers published in Age and Ageing since 2011 cover key themes in cardiovascular ageing, with a separate collection on stroke and atrial fibrillation planned. Treating high blood pressure remains important as people age and reduces strokes and heart attacks. That said, a more personalised approach to blood pressure may be even more important as people age to lower blood pressure to tight targets where appropriate but avoid overtreatment in vulnerable groups. As people age, more people experience blood pressure drops on standing (orthostatic hypotension), particularly as they become frail. This can predispose them to falls. The papers in this collection provide an insight into blood pressure and orthostatic hypotension. They highlight areas for further research to understand blood pressure changes and management in the ageing population. Inpatient clinical care of older people with heart attacks differs from younger people in UK national audit data. People aged over 80 had improved outcomes in survival after heart attack over time, but had lower rates of specialist input from cardiology compared with younger people. This may partly reflect different clinical presentations, with heart attacks occurring in the context of other health conditions, frailty and multimorbidity. The care and outcomes of acute and chronic cardiovascular disease are impacted by the frailty and health status of an individual at baseline. The research included in this collection reinforces the wide variations in the ageing population and the necessity to focus on the individual needs and priorities, and provide a person-centred multidisciplinary approach to care.
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